Overview

  • Multi-channel receive coil development: Design and development of 8-, 16- and possibly 32-channel MRI detection systems, both receive coils and receiver hardware.
  • SENSE imaging: Development of accelerated parallel imaging techniques and the software for image reconstruction, applied to increasing spatial resolution of MRI, as well as making single-shot fMRI at high field (> 3 T) feasible.
  • High-field (f)MRI: Pulse-sequence optimization for the NIH 7 T scanner, for high-resolution anatomical and functional imaging.
  • T1-based tissue separation: Creating grey-matter and white-matter selective anatomical images.
  • Development of perfusion-based fMRI: Comparing different labeling techniques and pulse seqences for increasing SNR and temporal resolution performance of perfusion-based fMRI, and comparing these methods to standard BOLD-fMRI.
  • Resting-state and early sleep fMRI, in combination with EEG or MEG: Characterizing resting-state brain activity during rest and early sleep stages. This can lead to further understanding of sleep processes and cortical connectivity.
  • Functional MRI of higher processing: Imaging the process of learning through standard psychological activation paradigms.